The multi-layered ASSIST tissue engineered model is a more recent technology development area at CPSI Biotech.  We have published extensively on this unique model and described the critical role it has played in the development and testing of several cryosurgical systems, as well as in the identification of promising cryoadjuvants.  Overall, the ASSIST platform provides a critical tool in bridging the gap from bench to bedside by reducing cost, time, and the need for extensive pre-clinical animal studies during the drug discovery, device development, and production verification and validation phases.